Anemia management without the guesswork
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A biomedical system dynamics approach to anemia management

PhySoftAMS is an individualized drug dosing platform that facilitates significant improvements in anemia and iron management for dialysis services providers.

PhySoftAMS accounts for the complexities of long- and short-acting ESAs and their effect on each patient’s unique response when creating red blood cells (the biological process of erythropoiesis), delivering personalized dosing recommendations that clinicians can trust.

Proven results

Shown to improve hemoglobin target achievement, reduce dosing variability, and lower ESA usage by nearly 50% in clinical trials and more than a decade of commercial use.

Individualized dosing

A doctor shows a patient his lab results.

Uses patient history to determine an individual’s hemoglobin response to ESAs, supporting recommendations that help reduce hemoglobin cycling, improve anemia control, and promote stable outcomes over time

Data-driven insights

Abstract view of a laptop showing medical data points.

Illuminates patient trends through clear graphic visualizations, enabling faster, more informed reviews that enhance efficiency, support clinical judgment, and improve care consistency across patient populations

Controlled access

A doctor interacts with a secure login screen on his laptop.

Provides convenient VPN-secured, HIPAA-compliant access through a browser or API, integrating seamlessly with EMRs to ensure patient data is protected while supporting efficient care delivery

Flexible configuration

A team of doctors and nurses collaborate at a conference table

Incorporates established protocols, preferences, and best practices, allowing care teams to benefit from the platform’s precision dosing while maintaining consistency with internal guidelines

Resource optimization

A pharmacist checks drug inventory against figures on a digital tablet.

Recommends the minimum drug amount needed to maintain patients’ hemoglobin within target ranges, helping reduce drug exposure, minimize waste, and support safer, more efficient anemia management

Managing anemia in dialysis patients is complex—and costly. Clinicians rely on PhySoftAMS to deliver ESA dosing with confidence. Here’s what some of them have to say about us.

“We started working with PhySoft to better manage our patients and the administration of ESAs. But now with the addition of systematic iron management, our patient outcomes have improved further, and our drug expenses are better managed.” "PhySoftAMS gives our organization a standardized approach to anemia management and ESA administration, no matter which clinician is providing care on the floor. Staff and shift rotations don’t alter our approach to anemia management because dosing recommendations are determined by PhySoft and the parameters we’ve chosen." "Using PhySoftAMS has enabled us to greatly improve our anemia management outcomes. We have provided our patients with more precise care, individualized to their treatment needs. And we’ve been able to improve and standardize care across all of our dialysis units. We recently have been able to centralize anemia management responsibilities, further improving consistency." “PhySoftAMS has given us a way to standardize ESA administration across units in Vermont and upstate New York. We now have a way to stabilize patient hemoglobin while using the minimum dose necessary of a medication that may have a negative impact at higher doses.” “Compared to how we were doing things before, using this system is a dream. I am so much more productive.” “Our collaboration with PhySoft over the years has helped us to improve patient outcomes, while reducing drug waste and streamlining our daily workflow. They provided custom reporting, helping us to eliminating hours of paperwork and manual calculations to maintain our drug inventories. PhySoft even stepped in to provide patient treatment continuity, when our EMR became inaccessible for weeks.” “I think of PhySoftAMS as an individualized protocol, which allows you to minimize cycling. And it does it efficiently. Another benefit … I’m no longer making frequent dose adjustments on most patients.”
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